Peptide Lab HQ Research Guide

AOD-9604

A research-focused compound profile covering AOD-9604 identity, hGH fragment research, lipolysis pathway studies, metabolic research models, concentration reference, reconstitution reference, and safety considerations.

Compound Profile

Compound Name AOD-9604
Compound Type Synthetic modified human growth hormone fragment
CAS Number 221231-10-3
PubChem CID 71300630
Amino Acid Length 16 amino acids
Amino Acid Sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Short Sequence YLRIVQCRSVEGSCGF
Molecular Formula C₇₈H₁₂₃N₂₃O₂₃S₂
Molecular Weight Approximately 1815.1 g/mol
Research Category hGH fragment, lipolysis, lipid metabolism, β-adrenergic pathway, metabolic, and body-composition research
Appearance White to off-white lyophilized powder
Use For laboratory research use only.

Key Research Applications

AOD-9604 is commonly discussed in controlled research models involving modified human growth hormone fragment activity, lipid metabolism, lipolysis pathway signaling, fat oxidation, body-composition endpoints, and metabolic-response documentation.

hGH Fragment Research

AOD-9604 is modeled from the C-terminal region of human growth hormone and is commonly studied as a modified fragment separate from full-length growth hormone.

Lipolysis Pathway Models

Used in research involving lipolytic signaling, lipid mobilization, fat-cell metabolism, and adipose tissue response models.

β-Adrenergic Pathway Context

Research literature discusses AOD-9604 in connection with β-adrenergic signaling, particularly β3-adrenergic receptor pathway context in metabolic models.

Body-Composition Research

AOD-9604 has been evaluated in body-weight and body-composition research contexts, including animal models and human clinical-study references.

Metabolic Research Models

Relevant to research involving lipid oxidation, energy balance, glucose-related markers, and broader metabolic-response documentation.

Safety / Tolerability Research

Human and animal studies have evaluated AOD-9604 safety and tolerability in controlled research settings, though this does not establish a universal research-use protocol.

Research Scope

These applications are provided for educational and research-reference purposes only. Research outcomes may vary based on study model, route, formulation, purity, concentration, and laboratory conditions.

Reconstitution / Research Dosing Reference

Select Reference Vial

Select a vial size to update the concentration, U-100 unit references, and frequency table below. This AOD-9604 reference uses a custom solvent system: 0.5 mL acetic acid followed by 2.5 mL bacteriostatic water.

Quick Reference Summary

Reference Vial 2 mg AOD-9604
Primary Solvent System 0.5 mL acetic acid + 2.5 mL bacteriostatic water
Total Solution Volume 3.0 mL total solution volume
Primary Concentration 0.67 mg/mL
Measurement Reference On a U-100 syringe, 1 unit = 0.01 mL.
Amount per U-100 Unit At 0.67 mg/mL, 1 unit equals 0.0067 mg / 6.67 mcg AOD-9604.
Storage Reference Refrigerate at 2–8°C / 35.6–46.4°F after preparation, protected from direct light.

Reconstitution Steps

  1. Draw 0.5 mL Acetic Acid using a sterile syringe or measured sterile preparation method.
  2. Slowly add the 0.5 mL acetic acid down the side of the vial wall.
  3. Gently roll or swirl the vial until the AOD-9604 material is fully wetted and begins dissolving. Do not shake!
  4. Draw 2.5 mL bacteriostatic water using a separate sterile syringe or measured sterile preparation method.
  5. Slowly add the 2.5 mL bacteriostatic water down the side of the vial wall to bring the total solution volume to 3.0 mL.
  6. Gently roll or swirl until the material is fully dissolved. The solution should appear clear to slightly hazy depending on concentration, supplier format, and solvent compatibility.
  7. Label with compound name, vial amount, solvent system, total solution volume, concentration, preparation date, storage conditions, and handling notes.
  8. Store refrigerated at 2–8°C / 35.6–46.4°F, protected from direct light.

Published Research Context

Reference Type Reported Amount / Context Research Notes
Compound Identity Reference AOD-9604, synthetic analogue of the lipolytic domain of human growth hormone AOD-9604 is commonly discussed as a modified C-terminal hGH fragment / hGH 176–191-related peptide in metabolic and lipid-marker research contexts.
Sequence Reference YLRIVQCRSVEGSCGF This sequence is commonly listed for AOD-9604 in chemical database and peptide reference contexts.
Solvent Compatibility Context Acetic acid pre-dissolution + bacteriostatic water dilution reference This page uses a custom solvent method where acetic acid is added first to assist dissolution, followed by bacteriostatic water to reach the final 3.0 mL reference volume.
Lipid-Metabolism Research Model-dependent concentration and endpoint tracking AOD-9604 has been discussed in lipid-metabolism, lipolysis, fat-oxidation, adipose-tissue, and metabolic-marker research models.
β3-Adrenergic Pathway Research Preclinical pathway context Published animal research has discussed AOD-9604 in relation to β3-adrenergic receptor pathway involvement, lipolytic sensitivity, and adipose-tissue response markers.
hGH Fragment Research Context Modified hGH C-terminal fragment context AOD-9604 is commonly distinguished from full human growth hormone because it is studied as a fragment-derived peptide rather than a full GH analog.
Clinical-Study Research Context Clinical-study context only AOD-9604 has appeared in human clinical-study discussions related to obesity and metabolic markers. These clinical-study contexts are not research-chemical dosing standards.
Public Protocol-Style Reference Microgram-to-milligram reference examples Public protocol-style references commonly describe AOD-9604 in microgram-to-milligram examples depending on the research model and preparation format. These are not clinical dosing standards.
Clinical / Research-Chemical Status No universal research-chemical protocol established Published study references, preclinical research references, public protocol-style references, clinical-study contexts, or wellness protocols should not be treated as dosing instructions for research-chemical vial formats.

Concentration Reference

Vial Amount Acetic Acid Bacteriostatic Water Total Solution Volume Final Concentration
2 mg 0.5 mL 2.5 mL 3.0 mL 0.67 mg/mL
5 mg 0.5 mL 2.5 mL 3.0 mL 1.67 mg/mL
10 mg 0.5 mL 2.5 mL 3.0 mL 3.33 mg/mL

Research Dosing Amount / Volume Reference

Reference Amount Volume at 0.67 mg/mL U-100 Unit Reference Approx. References per 2 mg Vial
50 mcg 0.075 mL 7.5 units 40
0.1 mg / 100 mcg 0.15 mL 15 units 20
0.25 mg / 250 mcg 0.375 mL 37.5 units 8
0.5 mg / 500 mcg 0.75 mL 75 units 4
1 mg / 1000 mcg 1.50 mL 150 units 2
2 mg / 2000 mcg 3.00 mL 300 units 1
5 mg / 5000 mcg 7.50 mL 750 units 0.4
10 mg / 10000 mcg 15.00 mL 1500 units 0.2

Research Frequency / Amount Reference

Research Window Frequency Reference Amount Units / Volume Reference
Lower Microgram Reference Calculation reference only 50 mcg reference amount 7.5 units / 0.075 mL
Standard Microgram Reference Calculation reference only 0.1 mg reference amount 15 units / 0.15 mL
Low Milligram Conversion Example Public protocol-style reference, not a clinical dosing standard 250 mcg reference amount 37.5 units / 0.375 mL
Mid-Range Conversion Example Public protocol-style reference, not a clinical dosing standard 0.5 mg reference amount 75 units / 0.75 mL
Upper Conversion Example Calculation reference only 1 mg reference amount 150 units / 1.50 mL
2 mg Preparation Reference Preparation-level calculation reference 2 mg reference amount 300 units / 3.00 mL
5 mg Preparation Reference Preparation-level calculation reference 5 mg reference amount 750 units / 7.50 mL
10 mg Preparation Reference Preparation-level calculation reference 10 mg reference amount 1500 units / 15.00 mL

Common Research Windows

Reference Window Common Length Research Notes
Cell-Culture / Metabolic Marker Window 24–72 hours May be used for lipid-metabolism marker, adipocyte-response, lipolysis marker, beta-adrenergic pathway, or cellular-response documentation depending on the model.
Acute Metabolic Observation Window Single session to several days Used for short-term fat-oxidation marker comparison, adipose-tissue response tracking, metabolic-marker observation, or early pathway documentation depending on the research design.
Short Research Window 1–4 weeks May be used for early controlled observation involving lipid markers, adipose-tissue markers, metabolic markers, or body-composition model endpoints.
Standard Protocol-Style Window 4–8 weeks Commonly used in public protocol-style references for structured observation and comparison across baseline and follow-up periods.
Extended Observation Window 8–12 weeks or longer Used when longer documentation is needed for metabolic-marker trends, body-composition markers, lipid-marker comparison, or follow-up marker tracking.
Follow-Up / Washout 2–8 weeks Used to document post-study observations, marker return, delayed response patterns, or follow-up data depending on the research model.

Research Note: These tables are provided for educational, research-planning, concentration, frequency-reference, and volume-reference purposes only. AOD-9604 is commonly discussed in modified hGH fragment, hGH 176–191-related, lipid-metabolism, lipolysis, fat-oxidation, adipose-tissue, beta-adrenergic pathway, metabolic-marker, and body-composition research contexts. This custom reference uses 0.5 mL acetic acid followed by 2.5 mL bacteriostatic water for a total solution volume of 3.0 mL across the 2 mg, 5 mg, and 10 mg vial references. Final concentration changes by vial amount: 2 mg = 0.67 mg/mL, 5 mg = 1.67 mg/mL, and 10 mg = 3.33 mg/mL. Solvent compatibility, solubility, and handling should be verified against the COA, batch record, or formula record when available. Published study references, clinical-study contexts, preclinical research references, and public protocol-style frequency references are not universal research-chemical dosing standards and should not be treated as dosing instructions for research-chemical vial formats. This information is not medical advice, dosing instruction, injectable-use guidance, or a recommendation for human or animal use.

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Research Findings & Safety Notes

Research Findings

AOD-9604 is commonly discussed in research involving lipolysis, lipid metabolism, body-composition endpoints, β-adrenergic pathway interaction, and metabolic-response documentation.

Study Limitations

AOD-9604 research includes animal studies, oral human clinical-study references, and safety reviews. Findings should be interpreted according to route, formulation, study duration, and research model.

Safety Considerations

Laboratory handling should include appropriate PPE, sterile technique, proper labeling, batch documentation, and qualified research procedures.

Use Restriction

Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease when discussed as a research-use material.

Research Supplies

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Bacteriostatic Water

Bacteriostatic Water

Commonly referenced in laboratory preparation workflows.

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Research Syringes

Research Syringes

Supply category for controlled laboratory research preparation.

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Prep Supplies

Prep Supplies

Supporting supplies for clean handling, preparation, and documentation.

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Handling & Storage

Storage

Store materials according to product-specific requirements. Protect from excessive heat, moisture, and direct light.

After Reconstitution

Keep refrigerated after reconstitution unless otherwise specified by the product documentation.

Handling

Use appropriate laboratory PPE, clean handling practices, and qualified research procedures.

Documentation

Maintain batch details, COA records, preparation notes, and internal research documentation.

Research Use Disclaimer: PeptideLabHQ content is provided for educational and informational purposes only. This information is not medical advice and is not intended to diagnose, treat, cure, or prevent any disease. Materials discussed are intended strictly for laboratory research use only and are not for human or animal consumption.