Peptide Lab HQ Research Guide
Hexarelin
A research-focused compound profile covering Hexarelin identity, GHRP-6 analog research, ghrelin receptor / growth hormone secretagogue activity, GH-axis signaling, concentration reference, reconstitution reference, and safety considerations.
Compound Data
Compound Profile
| Compound Name | Hexarelin |
|---|---|
| Common Name | Examorelin |
| Common Synonyms | Hexarelin acetate, Examorelin, HEX, GHRP-6 analog, growth hormone-releasing peptide analog |
| Compound Type | Synthetic hexapeptide / growth hormone secretagogue research peptide |
| CAS Number | 140703-51-1; verify against supplier COA |
| PubChem CID | 6918297 |
| Amino Acid Length | 6 amino acids |
| Amino Acid Sequence | His-D-2-Me-Trp-Ala-Trp-D-Phe-Lys-NH₂ |
| Structural Feature | GHRP-6-related hexapeptide containing D-amino acid substitutions and 2-methyltryptophan modification |
| Molecular Formula | C₄₇H₅₈N₁₂O₆; verify against supplier COA |
| Molecular Weight | Approximately 887.0–887.04 g/mol; verify against supplier COA |
| Research Category | Growth hormone secretagogue, GHSR pathway, ghrelin receptor research, GH-axis signaling, pituitary response, endocrine-marker research, and HPA-axis context |
| Research Context | Commonly discussed in controlled research involving GH release, pituitary signaling, ghrelin receptor pathway activity, GHRH interaction models, prolactin response, cortisol response, and endocrine biomarker documentation. |
| Appearance | White to off-white lyophilized powder, depending on supplier documentation |
| Use | For laboratory research use only. |
Research Applications
Key Research Applications
Hexarelin is commonly discussed in controlled research models involving growth hormone secretagogue activity, ghrelin receptor / GHSR pathway signaling, pituitary GH release, GHRH interaction models, endocrine-marker response, prolactin response, cortisol response, and HPA-axis research context.
Growth Hormone Secretagogue Research
Hexarelin is studied as a synthetic GH-releasing peptide that stimulates growth hormone release through growth hormone secretagogue pathway activity.
Ghrelin Receptor / GHSR Models
Used in research involving ghrelin receptor-related signaling, GHSR pathway activity, and GH secretagogue receptor response.
Pituitary GH-Release Research
Hexarelin appears in studies evaluating pituitary GH release, dose-response curves, timing of GH peaks, and endocrine-marker tracking.
GHRH Interaction Models
Research has evaluated Hexarelin alone and in combination with GHRH to compare GH-axis response and pathway interaction.
HPA-Axis Context
Hexarelin research includes cortisol, ACTH, and prolactin response observations, making HPA-axis context important for safety discussion.
Endocrine Biomarker Research
Relevant study markers include GH response, IGF-1 context, prolactin, cortisol, ACTH, glucose-related markers, and broader endocrine feedback observations.
Research Scope
These applications are provided for educational and research-reference purposes only. Research outcomes may vary based on peptide form, purity, concentration, route, receptor expression, baseline endocrine status, study design, and laboratory conditions.
Reference Only
Reconstitution / Research Dosing Reference
Select Reference Vial
Select a vial size to update the concentration, U-100 unit references, and frequency table below.
Quick Reference Summary
| Reference Vial | 2 mg Hexarelin |
|---|---|
| Primary Solution Volume | 2 mL bacteriostatic water |
| Primary Concentration | 1 mg/mL |
| Measurement Reference | On a U-100 syringe, 1 unit = 0.01 mL. |
| Amount per U-100 Unit | At 1 mg/mL, 1 unit equals 0.01 mg / 10 mcg Hexarelin. |
| Storage Reference | Refrigerate at 2–8°C / 35.6–46.4°F after reconstitution, protected from direct light. |
Reconstitution Steps
- Draw 2 mL bacteriostatic water using a sterile syringe for the main concentration reference shown below.
- Slowly add the BAC water down the side of the vial wall.
- Gently roll or swirl the vial until the material is completely dissolved. The solution should appear clear. Do not shake!
- Label with compound name, vial amount, concentration, solvent volume, preparation date, storage conditions, and handling notes.
- Store refrigerated at 2–8°C / 35.6–46.4°F, protected from direct light.
Published Research Context
| Reference Type | Reported Amount / Context | Research Notes |
|---|---|---|
| Compound Identity Reference | Hexarelin, also known as examorelin | Hexarelin is commonly described as a synthetic GH-releasing hexapeptide in the growth hormone secretagogue / GHRP family. |
| GHRP-Family Research | Model-dependent concentration and endpoint tracking | Commonly discussed in growth hormone secretagogue, ghrelin-receptor, pituitary-response, and GH-release research contexts. |
| Neuroendocrine Marker Research | Model-dependent endocrine-marker tracking | Research discussions may involve GH, IGF-1 pathway context, prolactin, ACTH, cortisol, and hypothalamic-pituitary-axis markers. |
| Public Protocol-Style Reference | Microgram-range reference examples | Public protocol-style references are not clinical dosing standards and should not be treated as research-chemical use instructions. |
| Clinical / Research-Chemical Status | No universal research-chemical protocol established | Published study references, public protocol-style references, clinical-use references, or wellness protocols should not be treated as dosing instructions for research-chemical vial formats. |
Concentration Reference
| Vial Amount | Solution Volume | Final Concentration |
|---|---|---|
| 2 mg | 2 mL | 1 mg/mL |
| 5 mg | 2 mL | 2.5 mg/mL |
Research Dosing Amount / Volume Reference
| Reference Amount | Volume at 1 mg/mL | U-100 Unit Reference | Approx. References per 2 mg Vial |
|---|---|---|---|
| 50 mcg | 0.05 mL | 5 units | 40 |
| 0.1 mg / 100 mcg | 0.10 mL | 10 units | 20 |
| 0.2 mg / 200 mcg | 0.20 mL | 20 units | 10 |
| 0.25 mg / 250 mcg | 0.25 mL | 25 units | 8 |
| 0.5 mg / 500 mcg | 0.50 mL | 50 units | 4 |
| 1 mg / 1000 mcg | 1.00 mL | 100 units | 2 |
| 2 mg / 2000 mcg | 2.00 mL | 200 units | 1 |
| 5 mg / 5000 mcg | 5.00 mL | 500 units | 0.4 |
Research Frequency / Amount Reference
| Research Window | Frequency | Reference Amount | Units / Volume Reference |
|---|---|---|---|
| Lower Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 50 mcg reference amount | 5 units / 0.05 mL |
| Low-to-Mid Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 0.1 mg / 100 mcg reference amount | 10 units / 0.10 mL |
| Standard Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 0.2 mg / 200 mcg reference amount | 20 units / 0.20 mL |
| Mid-Range Conversion Example | Public protocol-style reference, not a clinical dosing standard | 0.25 mg / 250 mcg reference amount | 25 units / 0.25 mL |
| Upper Conversion Example | Public protocol-style reference, not a clinical dosing standard | 0.5 mg / 500 mcg reference amount | 50 units / 0.50 mL |
| High Conversion Example | Public protocol-style reference, not a clinical dosing standard | 1 mg / 1000 mcg reference amount | 100 units / 1.00 mL |
Common Research Windows
| Reference Window | Common Length | Research Notes |
|---|---|---|
| Cell-Culture / Marker Observation Window | 24–72 hours | May be used for receptor-response, pituitary-cell, GH-release, endocrine-marker, or cellular-signaling documentation depending on the model. |
| Acute Observation Window | Single session to several days | Used for short-term response tracking, timing comparison, early marker observation, or preparation comparison depending on the research design. |
| Short Research Window | 1–2 weeks | May be used for early controlled observation involving GH-release, IGF-1 pathway context, metabolic markers, or endocrine-response markers. |
| Standard Protocol-Style Window | 2–4 weeks | Commonly used in public protocol-style references for structured observation and comparison across baseline and follow-up periods. |
| Extended Observation Window | 4–8 weeks | Used when longer documentation is needed for endocrine-marker trends, receptor-response patterns, metabolic-marker comparison, or follow-up marker tracking. |
| Follow-Up / Washout | 1–4 weeks | Used to document post-study observations, marker return, delayed response patterns, or follow-up data depending on the research model. |
Research Note: These tables are provided for educational, research-planning, concentration, frequency-reference, and volume-reference purposes only. Hexarelin, also known as examorelin, is commonly discussed in growth hormone secretagogue, GHRP-family, ghrelin-receptor, pituitary-response, GH-release, neuroendocrine-marker, and metabolic-marker research contexts. The selector above updates calculations for 2 mg and 5 mg vial references, each reconstituted with 2.0 mL bacteriostatic water. Published study references and public protocol-style frequency references are not universal research-chemical dosing standards and should not be treated as dosing instructions for research-chemical vial formats. This information is not medical advice, dosing instruction, injectable-use guidance, or a recommendation for human or animal use.
Research Notes
Research Findings & Safety Notes
Research Findings
Hexarelin is commonly discussed in research involving growth hormone secretagogue activity, ghrelin receptor / GHSR pathway signaling, pituitary GH release, GHRH interaction, prolactin response, cortisol response, ACTH response, and endocrine-marker tracking.
Study Limitations
Hexarelin research includes human endocrine studies, cell models, animal models, route-comparison research, and short-term repeated-exposure studies. Findings should be interpreted according to route, dose, peptide form, receptor expression, endocrine baseline, age, and study design.
Safety Considerations
Research discussion should account for GH / IGF-1 pathway activity, prolactin response, cortisol and ACTH response, glucose-related markers, appetite-related observations, cardiovascular response, peptide purity, sterility documentation, storage conditions, and qualified laboratory handling procedures.
Use Restriction
Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease when discussed as a research-use material.
Related Supplies
Research Supplies
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Bacteriostatic Water
Commonly referenced in laboratory preparation workflows.
Research Syringes
Supply category for controlled laboratory research preparation.
Prep Supplies
Supporting supplies for clean handling, preparation, and documentation.
Lab Handling
Handling & Storage
Storage
Store materials according to product-specific requirements. Protect from excessive heat, moisture, and direct light.
After Reconstitution
Keep refrigerated after reconstitution unless otherwise specified by the product documentation.
Handling
Use appropriate laboratory PPE, clean handling practices, and qualified research procedures.
Documentation
Maintain batch details, COA records, preparation notes, and internal research documentation.