Peptide Lab HQ Research Guide
SLU-PP-332
A research-focused compound profile covering SLU-PP-332 identity, estrogen-related receptor research, exercise-mimetic pathway models, metabolic research context, preparation reference, and safety considerations.
Compound Data
Compound Profile
| Compound Name | SLU-PP-332 |
|---|---|
| Chemical Name | 4-hydroxy-N-[(Z)-naphthalen-2-ylmethylideneamino]benzamide |
| Compound Type | Synthetic small-molecule estrogen-related receptor agonist |
| CAS Number | 303760-60-3 |
| PubChem CID | 5338394 |
| Molecular Formula | C₁₈H₁₄N₂O₂ |
| Molecular Weight | Approximately 290.3 g/mol |
| Research Category | ERRα, ERRβ, ERRγ, mitochondrial respiration, exercise-mimetic, metabolic syndrome, energy expenditure, and skeletal muscle research |
| Receptor Activity | Pan estrogen-related receptor agonist with reported EC₅₀ values of 98 nM, 230 nM, and 430 nM for ERRα, ERRβ, and ERRγ respectively. |
| Appearance | Solid research compound; verify physical appearance against supplier COA. |
| Use | For laboratory research use only. |
Research Applications
Key Research Applications
SLU-PP-332 is commonly discussed in controlled research models involving estrogen-related receptor activation, mitochondrial respiration, exercise-mimetic gene expression, skeletal muscle oxidative capacity, fatty-acid oxidation, energy expenditure, and metabolic syndrome research.
ERR Pathway Research
SLU-PP-332 is studied as a pan estrogen-related receptor agonist involving ERRα, ERRβ, and ERRγ pathway activity.
Exercise-Mimetic Models
Used in research involving aerobic exercise-like transcriptional programs, skeletal muscle adaptation, endurance markers, and oxidative fiber response.
Mitochondrial Research
Relevant to models evaluating mitochondrial respiration, mitochondrial DNA markers, cytochrome C, oxidative metabolism, and cellular energy output.
Metabolic Syndrome Models
SLU-PP-332 has been evaluated in high-fat-diet and metabolic syndrome mouse models involving body weight, fat mass, insulin sensitivity, and glucose tolerance.
Fatty-Acid Oxidation Research
Commonly discussed in research involving fatty-acid oxidation, energy expenditure, adipocyte size, lipid markers, and metabolic flexibility.
Aging & Organ Function Research
SLU-PP-332 has also been discussed in preclinical research involving age-related kidney dysfunction, mitochondrial markers, inflammation, and tissue response.
Research Scope
These applications are provided for educational and research-reference purposes only. Research outcomes may vary based on compound purity, solvent system, route, concentration, model type, metabolic status, and laboratory conditions.
Reference Only
Reconstitution / Research Dosing Reference
Quick Reference Summary
| Reference Vial | 5 mg SLU-PP-332 |
|---|---|
| Primary Solution Volume | 2.0 mL bacteriostatic water |
| Primary Concentration | 2.5 mg/mL |
| Measurement Reference | On a U-100 syringe, 1 unit = 0.01 mL. |
| Amount per U-100 Unit | At 2.5 mg/mL, 1 unit equals 0.025 mg / 25 mcg SLU-PP-332. |
| Storage Reference | Refrigerate at 2–8°C / 35.6–46.4°F after preparation, protected from direct light. |
Reconstitution Steps
- Draw 2.0 mL bacteriostatic water using a sterile syringe for the main concentration reference shown below.
- Slowly add the BAC water down the side of the vial wall.
- Gently roll or swirl the vial until the material is completely dissolved. The solution should appear clear to slightly hazy depending on concentration and supplier format. Do not shake!
- Because SLU-PP-332 is commonly referenced as a small-molecule research compound rather than a standard peptide, verify solvent compatibility, solubility, and handling notes against the supplier COA, batch record, or formula record when available.
- Label with compound name, vial amount, concentration, solvent volume, preparation date, storage conditions, and handling notes.
- Store refrigerated at 2–8°C / 35.6–46.4°F, protected from direct light, unless supplier documentation specifies otherwise.
Published Research Context
| Reference Type | Reported Amount / Context | Research Notes |
|---|---|---|
| Compound Identity Reference | SLU-PP-332 | SLU-PP-332 is commonly discussed as a synthetic estrogen-related receptor agonist chemical probe in exercise-mimetic and metabolic research contexts. |
| ERR Agonist Research | ERRα / ERRβ / ERRγ pathway context | Research discussions commonly describe SLU-PP-332 in relation to estrogen-related receptor activation, nuclear receptor signaling, and transcriptional regulation of energy-metabolism pathways. |
| Exercise-Mimetic Research Context | Preclinical and model-dependent context | SLU-PP-332 has been discussed in research involving exercise-mimetic signaling, aerobic-response markers, oxidative muscle fiber markers, endurance-model endpoints, and skeletal-muscle adaptation. |
| Mitochondrial / Metabolic Research | Model-dependent concentration and endpoint tracking | Commonly discussed in mitochondrial function, fatty-acid oxidation, glucose handling, energy expenditure, oxidative phosphorylation, and metabolic-homeostasis research contexts. |
| Metabolic Syndrome Research Context | Preclinical research context only | SLU-PP-332 has appeared in preclinical research involving metabolic syndrome, adiposity markers, insulin-related markers, lipid markers, and cardiometabolic model endpoints. |
| Public Protocol-Style Reference | Milligram-range reference examples | Public protocol-style references may describe SLU-PP-332 in milligram-range examples depending on the research model and preparation format. These are not clinical dosing standards. |
| Clinical / Research-Chemical Status | No universal research-chemical protocol established | Published study references, preclinical model references, public protocol-style references, wellness protocols, or public dosing pages should not be treated as dosing instructions for research-chemical vial formats. |
Concentration Reference
| Vial Amount | Solution Volume | Final Concentration |
|---|---|---|
| 5 mg | 2.0 mL | 2.5 mg/mL |
Research Dosing Amount / Volume Reference
| Reference Amount | Volume at 2.5 mg/mL | U-100 Unit Reference | Approx. References per 5 mg Vial |
|---|---|---|---|
| 50 mcg | 0.02 mL | 2 units | 100 |
| 100 mcg | 0.04 mL | 4 units | 50 |
| 0.25 mg / 250 mcg | 0.10 mL | 10 units | 20 |
| 0.5 mg / 500 mcg | 0.20 mL | 20 units | 10 |
| 1 mg / 1000 mcg | 0.40 mL | 40 units | 5 |
| 2 mg / 2000 mcg | 0.80 mL | 80 units | 2.5 |
| 5 mg / 5000 mcg | 2.00 mL | 200 units | 1 |
Research Frequency / Amount Reference
| Research Window | Frequency | Reference Amount | Units / Volume Reference |
|---|---|---|---|
| Lower Microgram Reference | Calculation reference only | 50 mcg reference amount | 2 units / 0.02 mL |
| Standard Microgram Reference | Calculation reference only | 100 mcg reference amount | 4 units / 0.04 mL |
| Low Milligram Conversion Example | Public protocol-style reference, not a clinical dosing standard | 250 mcg reference amount | 10 units / 0.10 mL |
| Mid-Range Conversion Example | Public protocol-style reference, not a clinical dosing standard | 0.5 mg reference amount | 20 units / 0.20 mL |
| Upper Conversion Example | Calculation reference only | 1 mg reference amount | 40 units / 0.40 mL |
| High Conversion Example | Calculation reference only | 2 mg reference amount | 80 units / 0.80 mL |
| Full-Vial Preparation Reference | Preparation-level calculation reference | 5 mg reference amount | 200 units / 2.00 mL |
Common Research Windows
| Reference Window | Common Length | Research Notes |
|---|---|---|
| Cell-Culture / Nuclear Receptor Window | 24–72 hours | May be used for ERR pathway activation, transcriptional-response markers, mitochondrial gene-expression markers, oxidative-metabolism markers, or cellular energy-pathway documentation depending on the model. |
| Acute Metabolic Observation Window | Single session to several days | Used for short-term metabolic-marker comparison, mitochondrial-response observation, oxidative-phosphorylation markers, or early pathway tracking depending on the research design. |
| Short Research Window | 1–2 weeks | May be used for early controlled observation involving oxidative muscle-fiber markers, fatty-acid oxidation markers, glucose-handling markers, or energy-metabolism endpoints. |
| Standard Protocol-Style Window | 2–4 weeks | Commonly used in public protocol-style references for structured observation and comparison across baseline and follow-up periods. |
| Extended Observation Window | 4–8 weeks | Used when longer documentation is needed for metabolic-marker trends, skeletal-muscle adaptation markers, mitochondrial-function markers, or cardiometabolic marker tracking. |
| Follow-Up / Washout | 1–4 weeks | Used to document post-study observations, marker return, delayed response patterns, or follow-up data depending on the research model. |
Research Note: These tables are provided for educational, research-planning, concentration, frequency-reference, and volume-reference purposes only. SLU-PP-332 is commonly discussed in estrogen-related receptor, ERRα / ERRβ / ERRγ, exercise-mimetic, mitochondrial-function, oxidative muscle-fiber, fatty-acid oxidation, glucose-handling, energy-metabolism, metabolic-syndrome, and cardiometabolic research contexts. This reference uses a 5 mg vial reconstituted with 2.0 mL bacteriostatic water, creating a 2.5 mg/mL concentration. Because SLU-PP-332 is commonly referenced as a small-molecule research compound rather than a standard peptide, solvent compatibility and solubility should be verified against the supplier COA, batch record, or formula record when available. Published study references, preclinical model references, and public protocol-style frequency references are not universal research-chemical dosing standards and should not be treated as dosing instructions for research-chemical vial formats. This information is not medical advice, dosing instruction, injectable-use guidance, or a recommendation for human or animal use.
Research Notes
Research Findings & Safety Notes
Research Findings
SLU-PP-332 is commonly discussed in research involving pan-ERR activation, mitochondrial respiration, aerobic exercise-like gene expression, oxidative skeletal muscle fiber response, energy expenditure, fatty-acid oxidation, glucose tolerance, and metabolic syndrome models.
Study Limitations
SLU-PP-332 research is primarily preclinical and tool-compound based. Findings should be interpreted according to model type, route, solvent system, exposure level, metabolic status, and study duration.
Safety Considerations
Research discussion should account for small-molecule solvent compatibility, purity, storage requirements, SDS review, compound stability, hazardous-material handling, route-specific uncertainty, and qualified laboratory procedures.
Use Restriction
Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease when discussed as a research-use material.
Related Supplies
Research Supplies
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Bacteriostatic Water
Commonly referenced in laboratory preparation workflows.
Research Syringes
Supply category for controlled laboratory research preparation.
Prep Supplies
Supporting supplies for clean handling, preparation, and documentation.
Lab Handling
Handling & Storage
Storage
Store materials according to product-specific requirements. Protect from excessive heat, moisture, and direct light.
After Reconstitution
Keep refrigerated after reconstitution unless otherwise specified by the product documentation.
Handling
Use appropriate laboratory PPE, clean handling practices, and qualified research procedures.
Documentation
Maintain batch details, COA records, preparation notes, and internal research documentation.