Peptide Lab HQ Research Guide
Epithalon
A research-focused compound profile covering Epithalon identity, AEDG tetrapeptide research, telomerase and telomere biology models, pineal peptide signaling, concentration reference, reconstitution reference, and safety considerations.
Compound Data
Compound Profile
| Compound Name | Epithalon |
|---|---|
| Common Synonyms | Epitalon, Epithalone, AEDG, Ala-Glu-Asp-Gly |
| Compound Type | Synthetic tetrapeptide / pineal peptide research analog |
| CAS Number | 307297-39-8 |
| PubChem CID | 219042 |
| Amino Acid Length | 4 amino acids |
| Amino Acid Sequence | Ala-Glu-Asp-Gly |
| Short Sequence | AEDG |
| Molecular Formula | C₁₄H₂₂N₄O₉ |
| Molecular Weight | Approximately 390.35 g/mol |
| Research Category | Telomerase, telomere biology, pineal peptide, aging, antioxidant, neuroendocrine, and cellular stress-response research |
| Appearance | White to off-white lyophilized powder |
| Use | For laboratory research use only. |
Research Applications
Key Research Applications
Epithalon is commonly discussed in controlled research models involving telomerase activity, telomere biology, pineal peptide signaling, age-related cellular changes, antioxidant response, neuroendocrine regulation, and cellular stress-response pathways.
Telomerase Research
Epithalon is commonly studied in cell-culture models involving telomerase expression, telomerase activity, and telomere maintenance pathways.
Telomere Biology Models
Used in research involving telomere length, cellular replication markers, chromatin activity, and aging-associated cellular changes.
Pineal Peptide Research
Epithalon is commonly discussed as a synthetic pineal tetrapeptide analog related to research involving pineal gland signaling and neuroendocrine regulation.
Antioxidant Response Models
Appears in research involving oxidative stress, ROS-related markers, mitochondrial response, and cellular protection models.
Aging Research Context
Used in animal and cell-based research models involving age-related biomarkers, cellular function, chromosome stability, and longevity-associated observations.
Retina / Brain / CNS Models
Epithalon has been discussed in research involving retina, brain, and pineal gland regulation, as well as broader neuroendocrine peptide signaling.
Research Scope
These applications are provided for educational and research-reference purposes only. Research outcomes may vary based on study model, timing, peptide purity, concentration, route, and laboratory conditions.
Reference Only
Reconstitution / Research Dosing Reference
Select Reference Vial
Select a vial size to update the concentration, U-100 unit references, and frequency table below.
Quick Reference Summary
| Reference Vial | 10 mg Epithalon |
|---|---|
| Primary Solution Volume | 2 mL bacteriostatic water |
| Primary Concentration | 5 mg/mL |
| Measurement Reference | On a U-100 syringe, 1 unit = 0.01 mL. |
| Amount per U-100 Unit | At 5 mg/mL, 1 unit equals 0.05 mg / 50 mcg Epithalon. |
| Storage Reference | Refrigerate at 2–8°C / 35.6–46.4°F after reconstitution, protected from direct light. |
Reconstitution Steps
- Draw 2 mL bacteriostatic water using a sterile syringe for the main concentration reference shown below.
- Slowly add the BAC water down the side of the vial wall.
- Gently roll or swirl the vial until the material is completely dissolved. The solution should appear clear. Do not shake!
- Label with compound name, vial amount, concentration, solvent volume, preparation date, storage conditions, and handling notes.
- Store refrigerated at 2–8°C / 35.6–46.4°F, protected from direct light.
Published Research Context
| Reference Type | Reported Amount / Context | Research Notes |
|---|---|---|
| Compound Identity Reference | Epithalon, also referenced as Epitalon / Ala-Glu-Asp-Gly | Epithalon is commonly discussed as a synthetic tetrapeptide in pineal peptide, cellular-aging, and telomerase-associated research contexts. |
| Pineal Peptide Research | Model-dependent concentration and endpoint tracking | Research discussions commonly include pineal peptide signaling, circadian-pattern, melatonin-related, and neuroendocrine marker contexts. |
| Telomerase / Cellular-Aging Research | Cellular-aging and telomere-associated model context | Epithalon is commonly discussed in relation to telomerase activity, telomere-length observations, senescence markers, and age-associated cellular pathways. |
| Public Protocol-Style Reference | Milligram-range reference examples | Public protocol-style references are not clinical dosing standards and should not be treated as research-chemical use instructions. |
| Clinical / Research-Chemical Status | No universal research-chemical protocol established | Published study references, public protocol-style references, clinical-use references, or wellness protocols should not be treated as dosing instructions for research-chemical vial formats. |
Concentration Reference
| Vial Amount | Solution Volume | Final Concentration |
|---|---|---|
| 10 mg | 2 mL | 5 mg/mL |
| 50 mg | 3 mL | 16.67 mg/mL |
Research Dosing Amount / Volume Reference
| Reference Amount | Volume at 5 mg/mL | U-100 Unit Reference | Approx. References per 10 mg Vial |
|---|---|---|---|
| 0.5 mg / 500 mcg | 0.10 mL | 10 units | 20 |
| 1 mg / 1000 mcg | 0.20 mL | 20 units | 10 |
| 2 mg / 2000 mcg | 0.40 mL | 40 units | 5 |
| 5 mg / 5000 mcg | 1.00 mL | 100 units | 2 |
| 10 mg / 10000 mcg | 2.00 mL | 200 units | 1 |
| 20 mg / 20000 mcg | 4.00 mL | 400 units | 0.5 |
Research Frequency / Amount Reference
| Research Window | Frequency | Reference Amount | Units / Volume Reference |
|---|---|---|---|
| Lower Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 0.5 mg / 500 mcg reference amount | 10 units / 0.10 mL |
| Low-to-Mid Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 1 mg / 1000 mcg reference amount | 20 units / 0.20 mL |
| Standard Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 2 mg / 2000 mcg reference amount | 40 units / 0.40 mL |
| Mid-Range Conversion Example | Public protocol-style reference, not a clinical dosing standard | 5 mg / 5000 mcg reference amount | 100 units / 1.00 mL |
| Upper Conversion Example | Public protocol-style reference, not a clinical dosing standard | 10 mg / 10000 mcg reference amount | 200 units / 2.00 mL |
| High Conversion Example | Public protocol-style reference, not a clinical dosing standard | 20 mg / 20000 mcg reference amount | 400 units / 4.00 mL |
Common Research Windows
| Reference Window | Common Length | Research Notes |
|---|---|---|
| Cell-Culture / Marker Observation Window | 24–72 hours | May be used for telomerase-related, oxidative-stress-marker, cellular-aging, gene-expression, or pathway-response documentation depending on the model. |
| Acute Observation Window | Single session to several days | Used for short-term response tracking, timing comparison, early marker observation, or preparation comparison depending on the research design. |
| Short Research Window | 1–2 weeks | May be used for early controlled observation involving cellular-aging, pineal peptide, circadian, oxidative-stress-marker, or telomere-associated documentation. |
| Standard Protocol-Style Window | 2–4 weeks | Commonly used in public protocol-style references for structured observation and comparison across baseline and follow-up periods. |
| Extended Observation Window | 4–8 weeks | Used when longer documentation is needed for follow-up marker comparison, research-cycle observation, or post-study trend analysis. |
| Follow-Up / Washout | 1–4 weeks | Used to document post-study observations, marker return, delayed response patterns, or follow-up data depending on the research model. |
Research Note: These tables are provided for educational, research-planning, concentration, frequency-reference, and volume-reference purposes only. Epithalon, also referenced as Epitalon, is commonly discussed in pineal peptide, circadian-pattern, cellular-aging, oxidative-stress-marker, telomerase, and telomere-associated research contexts. The selector above updates calculations for 10 mg reconstituted with 2.0 mL bacteriostatic water and 50 mg reconstituted with 3.0 mL bacteriostatic water. Published study references and public protocol-style frequency references are not universal research-chemical dosing standards and should not be treated as dosing instructions for research-chemical vial formats. This information is not medical advice, dosing instruction, injectable-use guidance, or a recommendation for human or animal use.
Research Notes
Research Findings & Safety Notes
Research Findings
Epithalon is commonly discussed in research involving telomerase activity, telomere biology, chromatin behavior, pineal peptide signaling, antioxidant response, neuroendocrine markers, and age-related cellular changes.
Study Limitations
Epithalon research includes cell-culture models, animal studies, mechanistic studies, and older clinical references. Findings should be interpreted according to model type, route, formulation, timing, and study design.
Safety Considerations
Laboratory handling should include appropriate PPE, sterile technique, proper labeling, batch documentation, and qualified research procedures.
Use Restriction
Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease when discussed as a research-use material.
Related Supplies
Research Supplies
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Bacteriostatic Water
Commonly referenced in laboratory preparation workflows.
Research Syringes
Supply category for controlled laboratory research preparation.
Prep Supplies
Supporting supplies for clean handling, preparation, and documentation.
Lab Handling
Handling & Storage
Storage
Store materials according to product-specific requirements. Protect from excessive heat, moisture, and direct light.
After Reconstitution
Keep refrigerated after reconstitution unless otherwise specified by the product documentation.
Handling
Use appropriate laboratory PPE, clean handling practices, and qualified research procedures.
Documentation
Maintain batch details, COA records, preparation notes, and internal research documentation.