Peptide Lab HQ Research Guide

Glutathione

A research-focused compound profile covering Glutathione identity, antioxidant pathway research, redox biology, detoxification models, concentration reference, reconstitution reference, and safety considerations.

Compound Profile

Compound Name Glutathione
Common Form L-Glutathione, Reduced Glutathione, GSH
Compound Type Endogenous tripeptide / antioxidant research compound
CAS Number 70-18-8
PubChem CID 124886
Amino Acid Length 3 amino acids
Amino Acid Components Glutamic acid, cysteine, and glycine
Short Form GSH
Molecular Formula C₁₀H₁₇N₃O₆S
Molecular Weight Approximately 307.32 g/mol
Research Category Antioxidant, redox biology, oxidative stress, detoxification, mitochondrial, immune, and neurological research
Appearance White to off-white lyophilized powder
Use For laboratory research use only.

Compound Profile

Compound Name Glutathione
Common Form L-Glutathione, Reduced Glutathione, GSH
Compound Type Endogenous tripeptide / antioxidant research compound
CAS Number 70-18-8
PubChem CID 124886
Amino Acid Length 3 amino acids
Amino Acid Components Glutamic acid, cysteine, and glycine
Short Form GSH
Molecular Formula C₁₀H₁₇N₃O₆S
Molecular Weight Approximately 307.32 g/mol
Research Category Antioxidant, redox biology, oxidative stress, detoxification, mitochondrial, immune, and neurological research
Appearance White to off-white lyophilized powder
Use For laboratory research use only.

Reconstitution / Research Dosing Reference

Select Reference Vial

Select a vial size to update the concentration, U-100 unit references, and frequency table below.

Quick Reference Summary

Reference Vial 600 mg Glutathione
Primary Solution Volume 3 mL bacteriostatic water
Primary Concentration 200 mg/mL
Measurement Reference On a U-100 syringe, 1 unit = 0.01 mL.
Amount per U-100 Unit At 200 mg/mL, 1 unit equals 2 mg / 2000 mcg Glutathione.
Storage Reference Refrigerate at 2–8°C / 35.6–46.4°F after reconstitution, protected from direct light.

Reconstitution Steps

  1. Draw 3 mL bacteriostatic water using a sterile syringe for the main concentration reference shown below.
  2. Slowly add the BAC water down the side of the vial wall.
  3. Gently roll or swirl the vial until the material is completely dissolved. The solution should appear clear to slightly hazy depending on concentration and supplier format. Do not shake!
  4. Label with compound name, vial amount, concentration, solvent volume, preparation date, storage conditions, and handling notes.
  5. Store refrigerated at 2–8°C / 35.6–46.4°F, protected from direct light.

Published Research Context

Reference Type Reported Amount / Context Research Notes
Compound Identity Reference Glutathione, commonly abbreviated GSH in its reduced form Glutathione is commonly discussed as a tripeptide composed of glutamate, cysteine, and glycine.
Antioxidant / Redox Research GSH / GSSG ratio and cellular redox-state context Research discussions commonly include antioxidant defense, oxidative-stress markers, reactive oxygen species, and cellular redox balance.
Detoxification / Enzyme Cofactor Research Model-dependent exposure Glutathione is commonly discussed as a cofactor for glutathione-dependent enzymes and cellular detoxification systems.
Public Protocol-Style Reference Milligram-range reference examples Public protocol-style references are not clinical dosing standards and should not be treated as research-chemical use instructions.
Clinical / Research-Chemical Status No universal research-chemical protocol established Published study references, public protocol-style references, clinical-use references, or wellness protocols should not be treated as dosing instructions for research-chemical vial formats.

Concentration Reference

Vial Amount Solution Volume Final Concentration
600 mg 3 mL 200 mg/mL
1200 mg 3 mL 400 mg/mL
1500 mg 3 mL 500 mg/mL

Research Dosing Amount / Volume Reference

Reference Amount Volume at 200 mg/mL U-100 Unit Reference Approx. References per 600 mg Vial
25 mg / 25000 mcg 0.12 mL 12.5 units 24
50 mg / 50000 mcg 0.25 mL 25 units 12
100 mg / 100000 mcg 0.50 mL 50 units 6
200 mg / 200000 mcg 1.00 mL 100 units 3
300 mg / 300000 mcg 1.50 mL 150 units 2
600 mg / 600000 mcg 3.00 mL 300 units 1
1200 mg / 1200000 mcg 6.00 mL 600 units 0.5
1500 mg / 1500000 mcg 7.50 mL 750 units 0.4

Research Frequency / Amount Reference

Research Window Frequency Reference Amount Units / Volume Reference
Lower Conversion Reference Public protocol-style reference, not a clinical dosing standard 50 mg / 50000 mcg reference amount 25 units / 0.25 mL
Low-to-Mid Conversion Reference Public protocol-style reference, not a clinical dosing standard 100 mg / 100000 mcg reference amount 50 units / 0.50 mL
Standard Conversion Reference Public protocol-style reference, not a clinical dosing standard 200 mg / 200000 mcg reference amount 100 units / 1.00 mL
Mid-Range Conversion Example Public protocol-style reference, not a clinical dosing standard 300 mg / 300000 mcg reference amount 150 units / 1.50 mL
Upper Conversion Example Public protocol-style reference, not a clinical dosing standard 600 mg / 600000 mcg reference amount 300 units / 3.00 mL
High Conversion Example Public protocol-style reference, not a clinical dosing standard 1200 mg / 1200000 mcg reference amount 600 units / 6.00 mL

Common Research Windows

Reference Window Common Length Research Notes
Cell-Culture / Marker Observation Window 24–72 hours May be used for oxidative-stress-marker, antioxidant-pathway, redox-state, cellular-response, or detoxification-enzyme documentation depending on the model.
Acute Observation Window Single session to several days Used for short-term response tracking, timing comparison, early marker observation, or preparation comparison depending on the research design.
Short Research Window 1–2 weeks May be used for early controlled observation involving oxidative-stress markers, GSH / GSSG balance, inflammatory-marker context, or cellular-resilience endpoints.
Standard Protocol-Style Window 2–4 weeks Commonly used in public protocol-style references for structured observation and comparison across baseline and follow-up periods.
Extended Observation Window 4–8 weeks Used when longer documentation is needed for redox-state trends, oxidative-stress-marker comparison, cellular-aging context, or follow-up marker tracking.
Follow-Up / Washout 1–4 weeks Used to document post-study observations, marker return, delayed response patterns, or follow-up data depending on the research model.

Research Note: These tables are provided for educational, research-planning, concentration, frequency-reference, and volume-reference purposes only. Glutathione is commonly discussed in antioxidant, oxidative-stress-marker, detoxification-enzyme, cellular redox-state, mitochondrial stress, inflammatory-marker, and cellular-resilience research contexts. The selector above updates calculations for 600 mg, 1200 mg, and 1500 mg vial references, each reconstituted with 3.0 mL bacteriostatic water. Published study references and public protocol-style frequency references are not universal research-chemical dosing standards and should not be treated as dosing instructions for research-chemical vial formats. This information is not medical advice, dosing instruction, injectable-use guidance, or a recommendation for human or animal use.

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Research Findings & Safety Notes

Research Findings

Glutathione is commonly discussed in research involving antioxidant defense, intracellular redox balance, oxidative stress response, detoxification pathways, mitochondrial function, immune markers, and neurological study contexts.

Study Limitations

Glutathione research includes oral supplementation studies, IV study references, neurological research, and biomarker models. Findings should be interpreted according to route, formulation, purity, stability, study population, and endpoint selection.

Safety Considerations

Glutathione materials intended for sterile research workflows should be evaluated for purity, endotoxin risk, sterility documentation, supplier qualification, batch records, and proper laboratory handling.

Use Restriction

Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease when discussed as a research-use material.

Research Supplies

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Bacteriostatic Water

Bacteriostatic Water

Commonly referenced in laboratory preparation workflows.

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Research Syringes

Research Syringes

Supply category for controlled laboratory research preparation.

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Prep Supplies

Prep Supplies

Supporting supplies for clean handling, preparation, and documentation.

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Handling & Storage

Storage

Store materials according to product-specific requirements. Protect from excessive heat, moisture, and direct light.

After Reconstitution

Keep refrigerated after reconstitution unless otherwise specified by the product documentation.

Handling

Use appropriate laboratory PPE, clean handling practices, and qualified research procedures.

Documentation

Maintain batch details, COA records, preparation notes, and internal research documentation.

Research Use Disclaimer: PeptideLabHQ content is provided for educational and informational purposes only. This information is not medical advice and is not intended to diagnose, treat, cure, or prevent any disease. Materials discussed are intended strictly for laboratory research use only and are not for human or animal consumption.