Peptide Lab HQ Research Guide
Pinealon
A research-focused compound profile covering Pinealon identity, EDR tripeptide research, neuroprotective pathway models, cognitive-function research context, concentration reference, preparation reference, and safety considerations.

Compound Data
Compound Profile
| Compound Name | Pinealon |
|---|---|
| Common Research Name | EDR tripeptide |
| Common Synonyms | Glu-Asp-Arg, H-Glu-Asp-Arg-OH, EDR peptide, T-33 peptide |
| Compound Type | Synthetic ultrashort tripeptide / peptide bioregulator research compound |
| CAS Number | 175175-23-2; verify against supplier COA |
| PubChem CID | 10273502 |
| Amino Acid Length | 3 amino acids |
| Amino Acid Sequence | Glu-Asp-Arg |
| Short Sequence | EDR |
| Molecular Formula | C₁₅H₂₆N₆O₈; verify against supplier COA |
| Molecular Weight | Approximately 418.41 g/mol; verify against supplier COA |
| Research Category | Peptide bioregulator, CNS model, neuroprotective pathway, cognitive-function, gene-expression, DNA interaction, oxidative-stress, and cellular aging-marker research |
| Research Context | Commonly discussed in ultrashort peptide bioregulator research involving neuronal function, neuroprotective signaling, cognitive-function models, DNA interaction, and gene-expression regulation. |
| Appearance | White to off-white lyophilized powder, depending on supplier documentation |
| Use | For laboratory research use only. |
Research Applications
Key Research Applications
Pinealon is commonly discussed in controlled research models involving EDR tripeptide signaling, neuroprotective pathway research, cognitive-function observations, gene-expression regulation, DNA interaction models, oxidative-stress response, and cellular aging-marker research.
Peptide Bioregulator Research
Pinealon is commonly positioned within ultrashort peptide bioregulator research, where short amino acid sequences are studied for tissue-specific signaling and gene-expression related effects.
CNS / Neuroprotective Models
EDR peptide research is commonly discussed in relation to neuronal function, neuroprotective pathways, and cellular-response models involving the nervous system.
Cognitive-Function Research
Pinealon has appeared in animal research involving spatial learning, memory retention, cognitive-function observations, and behavioral-response tracking.
Gene-Expression Context
EDR is discussed in research involving gene-expression activity, protein synthesis, transcriptional-response patterns, and short-peptide regulatory mechanisms.
DNA Interaction Research
Pinealon / EDR is commonly discussed in mechanistic research involving short-peptide interaction with DNA and chromatin-associated regulatory models.
Oxidative-Stress Models
Pinealon has been discussed in CNS oxidative-stress and antihypoxic research contexts involving neuronal resistance, cellular stress response, and protective pathway markers.
Research Scope
These applications are provided for educational and research-reference purposes only. Pinealon research is limited compared with major peptide categories, and outcomes may vary based on sequence identity, purity, study model, concentration, exposure duration, tissue model, and laboratory conditions.
Reference Only
Reconstitution / Research Dosing Reference
Select Reference Vial
Select a vial size to update the concentration, U-100 unit references, and frequency table below.
Quick Reference Summary
| Reference Vial | 5 mg Pinealon |
|---|---|
| Primary Solution Volume | 2 mL bacteriostatic water |
| Primary Concentration | 2.5 mg/mL |
| Measurement Reference | On a U-100 syringe, 1 unit = 0.01 mL. |
| Amount per U-100 Unit | At 2.5 mg/mL, 1 unit equals 0.025 mg / 25 mcg Pinealon. |
| Storage Reference | Refrigerate at 2–8°C / 35.6–46.4°F after reconstitution, protected from direct light. |
Reconstitution Steps
- Draw 2 mL bacteriostatic water using a sterile syringe for the main concentration reference shown below.
- Slowly add the BAC water down the side of the vial wall.
- Gently roll or swirl the vial until the material is completely dissolved. The solution should appear clear. Do not shake!
- Label with compound name, vial amount, concentration, solvent volume, preparation date, storage conditions, and handling notes.
- Store refrigerated at 2–8°C / 35.6–46.4°F, protected from direct light.
Published Research Context
| Reference Type | Reported Amount / Context | Research Notes |
|---|---|---|
| Compound Identity Reference | Pinealon, also referenced as EDR or Glu-Asp-Arg | Pinealon is commonly discussed as a synthetic tripeptide bioregulator made from glutamic acid, aspartic acid, and arginine. |
| Peptide Bioregulator Research | Model-dependent concentration and endpoint tracking | Commonly discussed in short-peptide bioregulator, DNA-interaction, gene-expression, cellular-response, and regulatory peptide contexts. |
| Neuroprotective / Cognitive Research | Experimental neural and cellular-stress model context | Research discussions commonly include neuronal-cell response, oxidative DNA damage, cognitive-function markers, and CNS response models. |
| Public Protocol-Style Reference | Milligram-range reference examples | Public protocol-style references are not clinical dosing standards and should not be treated as research-chemical use instructions. |
| Clinical / Research-Chemical Status | No universal research-chemical protocol established | Published study references, public protocol-style references, clinical-use references, or wellness protocols should not be treated as dosing instructions for research-chemical vial formats. |
Concentration Reference
| Vial Amount | Solution Volume | Final Concentration |
|---|---|---|
| 5 mg | 2 mL | 2.5 mg/mL |
| 10 mg | 2 mL | 5 mg/mL |
| 20 mg | 3 mL | 6.67 mg/mL |
Research Dosing Amount / Volume Reference
| Reference Amount | Volume at 2.5 mg/mL | U-100 Unit Reference | Approx. References per 5 mg Vial |
|---|---|---|---|
| 0.25 mg / 250 mcg | 0.10 mL | 10 units | 20 |
| 0.5 mg / 500 mcg | 0.20 mL | 20 units | 10 |
| 1 mg / 1000 mcg | 0.40 mL | 40 units | 5 |
| 2 mg / 2000 mcg | 0.80 mL | 80 units | 2.5 |
| 5 mg / 5000 mcg | 2.00 mL | 200 units | 1 |
| 10 mg / 10000 mcg | 4.00 mL | 400 units | 0.5 |
| 20 mg / 20000 mcg | 8.00 mL | 800 units | 0.2 |
Research Frequency / Amount Reference
| Research Window | Frequency | Reference Amount | Units / Volume Reference |
|---|---|---|---|
| Lower Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 0.25 mg / 250 mcg reference amount | 10 units / 0.10 mL |
| Low-to-Mid Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 0.5 mg / 500 mcg reference amount | 20 units / 0.20 mL |
| Standard Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 1 mg / 1000 mcg reference amount | 40 units / 0.40 mL |
| Mid-Range Conversion Example | Public protocol-style reference, not a clinical dosing standard | 2 mg / 2000 mcg reference amount | 80 units / 0.80 mL |
| Upper Conversion Example | Public protocol-style reference, not a clinical dosing standard | 5 mg / 5000 mcg reference amount | 200 units / 2.00 mL |
| High Conversion Example | Public protocol-style reference, not a clinical dosing standard | 10 mg / 10000 mcg reference amount | 400 units / 4.00 mL |
Common Research Windows
| Reference Window | Common Length | Research Notes |
|---|---|---|
| Cell-Culture / Marker Observation Window | 24–72 hours | May be used for gene-expression, oxidative-stress-marker, neuronal-cell response, DNA-damage, cellular-aging, or peptide-response documentation depending on the model. |
| Acute Observation Window | Single session to several days | Used for short-term response tracking, timing comparison, early marker observation, or preparation comparison depending on the research design. |
| Short Research Window | 1–2 weeks | May be used for early controlled observation involving cognitive-marker models, neural-response endpoints, oxidative-stress markers, or gene-expression documentation. |
| Standard Protocol-Style Window | 2–4 weeks | Commonly used in public protocol-style references for structured observation and comparison across baseline and follow-up periods. |
| Extended Observation Window | 4–8 weeks | Used when longer documentation is needed for neural-response trends, cellular-aging context, oxidative-stress-marker comparison, or follow-up marker tracking. |
| Follow-Up / Washout | 1–4 weeks | Used to document post-study observations, marker return, delayed response patterns, or follow-up data depending on the research model. |
Research Note: These tables are provided for educational, research-planning, concentration, frequency-reference, and volume-reference purposes only. Pinealon, also commonly referenced as EDR or Glu-Asp-Arg, is discussed in short-peptide bioregulator, neuroprotective, cognitive-function, oxidative-stress-marker, DNA-damage, gene-expression, cellular-aging, and central nervous system research contexts. The selector above updates calculations for 5 mg and 10 mg vial references reconstituted with 2.0 mL bacteriostatic water, and a 20 mg vial reference reconstituted with 3.0 mL bacteriostatic water. Published study references and public protocol-style frequency references are not universal research-chemical dosing standards and should not be treated as dosing instructions for research-chemical vial formats. This information is not medical advice, dosing instruction, injectable-use guidance, or a recommendation for human or animal use.
Research Notes
Research Findings & Safety Notes
Research Findings
Pinealon is commonly discussed in research involving ultrashort peptide bioregulation, EDR tripeptide signaling, CNS models, neuroprotective pathway research, cognitive-function observations, DNA interaction, gene-expression regulation, and oxidative-stress response.
Study Limitations
Pinealon research is limited compared with major peptide categories and includes peptide bioregulator, cell-culture, animal cognitive-function, gene-expression, and neuroprotective-model references. Findings should be interpreted according to peptide sequence, purity, model type, concentration, exposure duration, and endpoint selection.
Safety Considerations
Research discussion should account for peptide identity verification, EDR sequence confirmation, sterility documentation, endotoxin risk, supplier qualification, batch records, storage conditions, and qualified laboratory handling procedures.
Use Restriction
Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease when discussed as a research-use material.
Related Supplies
Research Supplies
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Bacteriostatic Water
Commonly referenced in laboratory preparation workflows.
Research Syringes
Supply category for controlled laboratory research preparation.
Prep Supplies
Supporting supplies for clean handling, preparation, and documentation.
Lab Handling
Handling & Storage
Storage
Store materials according to product-specific requirements. Protect from excessive heat, moisture, and direct light.
After Reconstitution
Keep refrigerated after reconstitution unless otherwise specified by the product documentation.
Handling
Use appropriate laboratory PPE, clean handling practices, and qualified research procedures.
Documentation
Maintain batch details, COA records, preparation notes, and internal research documentation.