Peptide Lab HQ Research Guide
Cardiogen
A research-focused compound profile covering Cardiogen identity, AEDR tetrapeptide research, peptide bioregulator models, cardiovascular tissue research context, concentration reference, preparation reference, and safety considerations.
Compound Data
Compound Profile
| Compound Name | Cardiogen |
|---|---|
| Common Research Name | AEDR tetrapeptide |
| Common Synonyms | Ala-Glu-Asp-Arg, H-Ala-Glu-Asp-Arg-OH, AEDR peptide, cardiovascular peptide bioregulator |
| Compound Type | Synthetic ultrashort tetrapeptide / peptide bioregulator research compound |
| PubChem CID | Commonly listed as 11583989; verify against supplier COA |
| Amino Acid Length | 4 amino acids |
| Amino Acid Sequence | Ala-Glu-Asp-Arg |
| Short Sequence | AEDR |
| Molecular Formula | C₁₈H₃₁N₇O₉; verify against supplier COA |
| Molecular Weight | Approximately 489.47–489.5 g/mol; verify against supplier COA |
| Research Category | Peptide bioregulator, cardiovascular tissue model, cardiomyocyte context, fibroblast activity, gene-expression, oxidative-stress, apoptosis-marker, and tissue-repair research |
| Research Context | Commonly discussed in ultrashort peptide bioregulator research involving cardiovascular tissue response, fibroblast activity, cardiomyocyte-associated models, DNA/histone interaction context, and cellular stress-response pathways. |
| Appearance | White to off-white lyophilized powder, depending on supplier documentation |
| Use | For laboratory research use only. |
Research Applications
Key Research Applications
Cardiogen is commonly discussed in controlled research models involving AEDR tetrapeptide activity, peptide bioregulation, cardiovascular tissue response, fibroblast activity, cardiomyocyte-associated models, gene-expression regulation, oxidative-stress response, and apoptosis-marker research.
Peptide Bioregulator Research
Cardiogen is commonly positioned within ultrashort peptide bioregulator research, where short amino acid sequences are studied for tissue-specific signaling and gene-expression related effects.
Cardiovascular Tissue Models
Cardiogen is commonly discussed in cardiovascular tissue research involving cellular proliferation, tissue-response observations, and cardiac-model documentation.
Fibroblast Activity Research
Public research references commonly frame Cardiogen around fibroblast activity, tissue-repair response, scar-formation context, and extracellular matrix observations.
Cardiomyocyte Context
Cardiogen is often discussed in cardiomyocyte-associated models involving cardiac cellular response, stress-response pathways, and cardiac tissue remodeling context.
DNA / Histone Interaction Research
AEDR is included among short peptides studied for histone-protein interaction and transcription-availability effects in peptide bioregulator research.
Oxidative-Stress & Apoptosis Models
Cardiogen research is commonly discussed around oxidative-stress response, DNA hydrolysis, cellular stress signaling, and apoptosis-marker observation.
Research Scope
These applications are provided for educational and research-reference purposes only. Cardiogen research is limited compared with major peptide categories, and outcomes may vary based on sequence identity, purity, study model, concentration, exposure duration, tissue model, and laboratory conditions.
Reference Only
Reconstitution / Research Dosing Reference
Quick Reference Summary
| Reference Vial | 20 mg Cardiogen |
|---|---|
| Primary Solution Volume | 1.0 mL bacteriostatic water |
| Primary Concentration | 20 mg/mL |
| Measurement Reference | On a U-100 syringe, 1 unit = 0.01 mL. |
| Amount per U-100 Unit | At 20 mg/mL, 1 unit equals 0.2 mg / 200 mcg Cardiogen. |
| Storage Reference | Refrigerate at 2–8°C / 35.6–46.4°F after reconstitution, protected from direct light. |
Reconstitution Steps
- Draw 1.0 mL bacteriostatic water using a sterile syringe for the main concentration reference shown below.
- Slowly add the BAC water down the side of the vial wall.
- Gently roll or swirl the vial until the material is completely dissolved. The solution should appear clear to slightly hazy depending on concentration and supplier format. Do not shake!
- Because this is a concentrated 20 mg/mL preparation, verify complete dissolution before recording final preparation details.
- Label with compound name, vial amount, concentration, solvent volume, preparation date, storage conditions, and handling notes.
- Store refrigerated at 2–8°C / 35.6–46.4°F, protected from direct light.
Published Research Context
| Reference Type | Reported Amount / Context | Research Notes |
|---|---|---|
| Compound Identity Reference | Cardiogen, commonly referenced as AEDR / Ala-Glu-Asp-Arg | Cardiogen is commonly discussed as a short synthetic tetrapeptide bioregulator associated with cardiovascular-tissue, cardiomyocyte, fibroblast, and tissue-specific regulatory research contexts. |
| Peptide Bioregulator Research | Model-dependent concentration and endpoint tracking | Commonly discussed in short-peptide bioregulator, DNA / chromatin interaction, gene-expression, cellular-response, and regulatory peptide research contexts. |
| Cardiovascular Tissue Research | Cardiomyocyte and cardiovascular-tissue model context | Cardiogen-related research discussions commonly include cardiomyocyte response, cardiovascular tissue markers, myocardial-cell proliferation, and cardiac-tissue regulatory observations. |
| Fibroblast / Tissue-Repair Research | Fibroblast and scar-formation model context | Public research discussions commonly reference fibroblasts, tissue-repair models, scar-formation context, extracellular-matrix markers, and tissue-remodeling observations. |
| Cellular Proliferation / p53 Research | Proliferation and apoptosis-marker context | Research discussions commonly include cellular-proliferation markers, p53 expression, apoptosis-associated markers, and age-related cellular-response observations depending on the model. |
| Oxidative-Stress Research Context | Cellular stress-response and tissue-protection context | Cardiogen is often discussed in relation to oxidative-stress markers, cellular-protection markers, inflammatory-marker context, and stress-response pathway documentation. |
| Gene-Expression Research Context | Short peptide / gene-expression marker context | Short peptide bioregulator literature commonly discusses DNA interaction, regulatory sequence context, chromatin structure, and changes in gene-expression marker patterns depending on the model. |
| Public Protocol-Style Reference | Milligram-range reference examples | Public protocol-style references commonly describe Cardiogen in milligram-range examples. These are not clinical dosing standards. |
| Clinical / Research-Chemical Status | No universal research-chemical protocol established | Published study references, public protocol-style references, clinical-use references, or wellness protocols should not be treated as dosing instructions for research-chemical vial formats. |
Concentration Reference
| Vial Amount | Solution Volume | Final Concentration |
|---|---|---|
| 20 mg | 1.0 mL | 20 mg/mL |
Research Dosing Amount / Volume Reference
| Reference Amount | Volume at 20 mg/mL | U-100 Unit Reference | Approx. References per 20 mg Vial |
|---|---|---|---|
| 0.5 mg / 500 mcg | 0.025 mL | 2.5 units | 40 |
| 1 mg / 1000 mcg | 0.05 mL | 5 units | 20 |
| 2 mg / 2000 mcg | 0.10 mL | 10 units | 10 |
| 5 mg / 5000 mcg | 0.25 mL | 25 units | 4 |
| 10 mg / 10000 mcg | 0.50 mL | 50 units | 2 |
| 20 mg / 20000 mcg | 1.00 mL | 100 units | 1 |
Research Frequency / Amount Reference
| Research Window | Frequency | Reference Amount | Units / Volume Reference |
|---|---|---|---|
| Lower Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 0.5 mg reference amount | 2.5 units / 0.025 mL |
| Standard Conversion Reference | Public protocol-style reference, not a clinical dosing standard | 1 mg reference amount | 5 units / 0.05 mL |
| Mid-Range Conversion Example | Calculation reference only | 2 mg reference amount | 10 units / 0.10 mL |
| Upper Conversion Example | Calculation reference only | 5 mg reference amount | 25 units / 0.25 mL |
| High Conversion Example | Calculation reference only | 10 mg reference amount | 50 units / 0.50 mL |
| Full-Vial Preparation Reference | Preparation-level calculation reference | 20 mg reference amount | 100 units / 1.00 mL |
Common Research Windows
| Reference Window | Common Length | Research Notes |
|---|---|---|
| Cell-Culture / Cardiovascular Marker Window | 24–72 hours | May be used for cardiomyocyte-response markers, fibroblast-response markers, oxidative-stress markers, proliferation markers, p53 marker observation, gene-expression, or peptide-response documentation depending on the model. |
| Acute Cardiac-Tissue Observation Window | Single session to several days | Used for early response tracking, cardiovascular-tissue marker comparison, oxidative-stress marker observation, or short-term pathway documentation depending on the research design. |
| Short Research Window | 1–2 weeks | May be used for short-duration controlled observation involving cardiomyocyte markers, fibroblast markers, tissue-remodeling markers, or gene-expression endpoints. |
| Standard Protocol-Style Window | 2–4 weeks | Commonly used in public protocol-style references for structured observation and comparison across baseline and follow-up periods. |
| Extended Observation Window | 4–8 weeks | Used when longer documentation is needed for cardiovascular-tissue marker trends, cellular-proliferation comparison, fibroblast-response tracking, or follow-up marker documentation. |
| Follow-Up / Washout | 1–4 weeks | Used to document post-study observations, marker return, delayed response patterns, or follow-up data depending on the research model. |
Research Note: These tables are provided for educational, research-planning, concentration, frequency-reference, and volume-reference purposes only. Cardiogen, commonly referenced as AEDR / Ala-Glu-Asp-Arg, is discussed in peptide bioregulator, cardiovascular-tissue, cardiomyocyte, fibroblast, tissue-repair, cellular-proliferation, p53 marker, oxidative-stress marker, gene-expression, and tissue-specific regulatory research contexts. This reference uses a 20 mg vial reconstituted with 1.0 mL bacteriostatic water, creating a 20 mg/mL concentration. Higher-concentration preparations may require supplier-specific handling, solvent-volume, or solubility notes; verify against the COA, batch record, or formula record when available. Published study references and public protocol-style frequency references are not universal research-chemical dosing standards and should not be treated as dosing instructions for research-chemical vial formats. This information is not medical advice, dosing instruction, injectable-use guidance, or a recommendation for human or animal use.
Research Notes
Research Findings & Safety Notes
Research Findings
Cardiogen is commonly discussed in research involving ultrashort peptide bioregulation, AEDR tetrapeptide signaling, cardiovascular tissue response, fibroblast activity, cardiomyocyte-associated models, DNA/histone interaction context, oxidative-stress response, and apoptosis-marker observations.
Study Limitations
Cardiogen research is limited compared with major peptide categories and includes peptide bioregulator, cardiac tissue, proliferation, DNA/histone interaction, and mechanistic research references. Findings should be interpreted according to peptide sequence, purity, model type, concentration, exposure duration, and endpoint selection.
Safety Considerations
Research discussion should account for peptide identity verification, AEDR sequence confirmation, sterility documentation, endotoxin risk, supplier qualification, batch records, storage conditions, and qualified laboratory handling procedures.
Use Restriction
Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease when discussed as a research-use material.
Related Supplies
Research Supplies
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Bacteriostatic Water
Commonly referenced in laboratory preparation workflows.
Research Syringes
Supply category for controlled laboratory research preparation.
Prep Supplies
Supporting supplies for clean handling, preparation, and documentation.
Lab Handling
Handling & Storage
Storage
Store materials according to product-specific requirements. Protect from excessive heat, moisture, and direct light.
After Reconstitution
Keep refrigerated after reconstitution unless otherwise specified by the product documentation.
Handling
Use appropriate laboratory PPE, clean handling practices, and qualified research procedures.
Documentation
Maintain batch details, COA records, preparation notes, and internal research documentation.